Transcranial random noise stimulation (tRNS) can enhance vision in the healthy and diseased brain.Yet, the impact of multi-day tRNS on large-scale cortical networks is still unknown.We investigated the impact of tRNS coupled with behavioral training on resting-state functional connectivity and attention.
We trained human subjects for 4 consecutive days on two attention tasks, while receiving tRNS over Speed Controller the intraparietal sulci, the middle temporal areas, or Sham stimulation.We measured resting-state functional connectivity of nodes of the dorsal and ventral attention network (DVAN) before and after training.We found a strong behavioral improvement and Horse Fly Sheets increased connectivity within the DVAN after parietal stimulation only.
Crucially, behavioral improvement positively correlated with connectivity measures.We conclude changes in connectivity are a marker for the enduring effect of tRNS upon behavior.Our results suggest that tRNS has strong potential to augment cognitive capacity in healthy individuals and promote recovery in the neurological population.